Welcome to the Xiaogen Lab!

Xiaogen Lab is dedicated to addressing fundamental problems in computational and structural biology, with a focus on atomic modeling from cryo-EM density maps, protein structure and function prediction, and gene editing analysis. We develop innovative computational tools by integrating artificial intelligence, machine learning, and bioinformatics to extract insights from large-scale biological data. We welcome undergraduate, master’s, and Ph.D. students with backgrounds in computer science, automation, mathematics, or bioinformatics. Each year, we admit around nine master’s students and 1–2 Ph.D. students.

News!

July 3, 2026, Prof. Xiaogen Zhou was invited to present a talk titled Assembly modeling of cryo-EM structures of protein complexes at the 2026 Artificial Intelligence and Biomedicine Ecosystem Conference in Shanghai, China.
June 27, 2026, Prof. Xiaogen Zhou was invited to present a talk titled Multi-scale assembly modeling of cryo-EM structures of protein complexes at the 4th National Academic Conference on Biomolecular Structure Prediction and Simulation in Qingdao, China.
January 14, 2026, invited by Nature Structural & Molecular Biology, Professor Xiaogen Zhou published a featured article titled When cryo-EM modeling meets structure prediction.
December 15, 2025, PhD student Zhang Ziying was selected for the Doctoral Student Special Program of the 2025 Young Science and Technology Talents Cultivation Project of the China Association for Science and Technology (CAST).
December 12, 2025, Master student Zou Jing and Master student Cai Yaxian were awarded the title of Excellent Master's Thesis of the College of Information Engineering, Zhejiang University of Technology.